AMA Journal of Ethics®

Illuminating the art of medicine

Journal of Ethics Header

AMA Journal of Ethics®

Illuminating the art of medicine

Virtual Mentor. April 2009, Volume 11, Number 4.

Ethics Poll

About Clinical Research Dollars and Results

The Ethics Poll is a snapshot of the opinions of interested readers.

Diseases in which category should have priority for allocation of U.S. funds for clinical research?

Institutional review boards (IRBs) are the bodies that must approve all proposed clinical research that involves human subjects. Should IRBs be required to have a member with expertise in medical ethics?

All federally funded clinical research or research on drugs that, if approved, will be regulated by the FDA must be listed with the NIH clinical trials registry before the research begins. The posting of trial outcomes to the registry is optional, and trials with positive outcomes are far more likely to be published in medical journals than those with negative, questionable, or nonsignificant outcomes. Federal regulations should be expanded to mandate that all trial outcomes be recorded in the registry.
Poll results reflect the opinions of visitors to the site who voluntarily answer the poll questions. Those visitors do not represent a random sample of our readers. The viewpoints expressed on this site are those of the authors and do not necessarily reflect the views and policies of the AMA.