This issue investigates how sleep is a communal natural resource and a basic physiological need that deserves our ethical attention and stewardship.

Racial and ethnic inequity exists throughout the lifespan, including at the end of life.

Whether and to what extent constitutional equal protection should apply to some nonhuman animals can be considered in light of corporations having gained such protection.

How to amend the 3 R’s has been driven mainly by philosophical ethics approaches to nonhuman animal rights and by scientific advancement.

Nonhuman animals used in biomedical research frequently suffer and are harmed as part of their use as experimental models.

A transition to organoids and organ-on-a-chip technologies would signal a paradigm shift in biomedical research.

Nonhuman animals have long been and continue to be routinely used in biomedical and behavioral research to promote human health. 

The possibility of nonhuman animals becoming legal persons and having better protections under the federal Animal Welfare Act is front and center here.

The American Medical Association was a major player in debates about vivisection in the late 1800s to mid-1950s.

Clinicians should know how randomized controlled trials can and cannot contribute to advancing health equity for transgender and gender diverse people.