AMA Journal of Ethics^®

A paradigm shift in circadian science is underway, exposing ethical tensions from a legacy of pervasive neglect of circadian disorders.

Behaviorally induced insufficient sleep syndrome can exacerbate morning side effects of prescription sleep aids, and there are potentially serious long-term risks.

A star-filled sky has long been a source of awe and inspiration, and its loss adversely affects human, nonhuman, and environmental health.

Fully assessing children’s sleep environments and effectively promoting children’s overall sleep health is nearly impossible during brief clinical encounters.

Dr Lauren Hale joins Ethics Talk to discuss sleep health and help us learn how we can all sleep better.

How to amend the 3 R’s has been driven mainly by philosophical ethics approaches to nonhuman animal rights and by scientific advancement.

Historically, most discussions about nonhuman animal experimentation consider what has become known as the 3 R’s: refinement, reduction, and replacement.

Ethically justifying human-centered research with only nonhuman animals as subjects likely requires that the research’s benefits to humans must, at least, outweigh harms suffered by the nonhuman animals.

Dr David DeGrazia joins Ethics Talk to discuss why the “3 R’s” of nonhuman animal research might not be sufficient to promote good science, ethics, and nonhuman animal welfare.

Humans make critical decisions about nonhuman lab animals outside the lab: during breeding, transportation, and end-of-study protocols.