Patients whose conditions are undiagnosed face stress and limited, delayed access to interventions that address their specific needs.

UDN research is complex and involves many variables, and some patient-subjects think that having enrolled in a UDN protocol was not worthwhile.

Dr Dónal O’Mathúna joins Ethics Talk to discuss his article, coauthored with Dr Nawaraj Upadhaya: “Should Children Be Enrolled in Clinical Research in Conflict Zones?”

Research that places subjects and investigators at risk of additional harm must be considered carefully.

Financial relationships are common, and ethical questions rightly emerge about how conflicts of interest compromise investigators’ approaches to research.

Clinician-researchers deeply invested in data gathering are still obliged to respect a patient-subject’s right to stop being in research.

In conducting research abroad, clinicians should treat community members with dignity and as research partners.

In conducting research abroad, clinicians should treat community members with dignity and as research partners.

Protecting patients rather than informed consent should be the goal when the complexity of information overwhelms patients’ decision-making capacity.

Advice for enrolling patients in clinical trials.