Clinical equipoise—the idea that the community of medical experts is uncertain about the relative therapeutic merits of the arms of a clinical trial at its outset—mitigates physicians’ responsibility for patients’ poor outcomes when patients are assigned to the control arm or are harmed by an investigational agent.
AMA J Ethics. 2015;17(12):1108-1115. doi:
10.1001/journalofethics.2015.17.12.ecas1-1512.
Elizabeth Lee Daugherty, MD, MPH and Douglas B. White, MD, MA
Opportunities to advance scientific knowledge may arise during humanitarian crises, but their presence does not justify suspension of the ethical foundations governing human subjects research.
Physicians can fulfill their professional responsibilities to patients when those responsibilities conflict with moral commitments of the hospital or clinic where the patient encounter occurs.
Frank A. Chervenak, MD and Laurence B. McCullough, PhD
Physicians can fulfill their professional responsibilities to patients when those responsibilities conflict with moral commitments of the hospital or clinic where the patient encounter occurs.