Vaccination rates among adolescents and young adults, for whom the risk of infection is greatest, remain lower than was true for other vaccines in their first years. And vaccination rates among males is extremely low.
AMA J Ethics. 2015;17(9):854-857. doi:
10.1001/journalofethics.2015.17.9.msoc1-1509.
Some commentators say comparative trials of FDA-approved drugs are overburdened by current Common Rule regulations and that researchers should not be required to obtain explicit consent for participation in the most innocuous of these trials.