The early diagnosis of Alzheimer disease is a boon in that it enables advance planning, but that planning process can engender conflict between respect for future-oriented autonomy and future welfare.
A consensus has emerged that the paternalism behind use of the provocative saline infusion test for nonepileptic seizures cannot be justified because the harms to the patient, the physician, and their relationship exceed the benefits.
Primary materials including interviews with some of the volunteer subjects provide information on the experiments into the pathogenic mechanism of yellow fever.
Physicians have a responsibility to assess elderly patients for conditions that could affect their ability to drive safely and to be familiar with state laws that govern physician duty to report impaired drivers.
Specific advocate guidelines are needed for the protection of children in state custody who are potential research subjects in trials that would expose them to greater-than-minimal risk but also hold the prospect of direct benefit.