Susanne Sheehy, BM BCh, MRCP, DTM&H and Joel Meyer, BM BCh, MRCP
The decline in numbers of healthy volunteers who participate in clinical trials has the potential to become a key rate-limiting factor in vaccine development.
Transgender people planning a medical transition face decisions about family planning, fertility preservation, and how to access gender-affirming treatment.
AMA J Ethics. 2016;18(11):1119-1125. doi:
10.1001/journalofethics.2016.18.11.pfor2-1611.
CBP researchers are challenged to think strategically about ways to convey their accomplishments and educate their non-CBPR peers about the nature of their research, processes not required of traditional researchers.
Research on emergency room patients with life-threatening illness, conducted under the FDA-approved Exception From Informed Consent (EFIC) policy, does not further reduce the autonomy of such patients and offers potential benefit to those patients as well as others.
Specific advocate guidelines are needed for the protection of children in state custody who are potential research subjects in trials that would expose them to greater-than-minimal risk but also hold the prospect of direct benefit.
Chris Feudtner, MD, PhD, MPH, David Munson, MD, and Wynne Morrison, MD
The way that we choose how to frame the conversation with parents about halting or continuing such therapy for their children who will not recover has special importance in medicine and in society.
In “Ethics of International Research: What Does Responsiveness Mean?” Christine Grady explains how developing countries are vulnerable to exploitation by researchers and explores what “responsiveness” to the needs of those populations might entail.