Specific advocate guidelines are needed for the protection of children in state custody who are potential research subjects in trials that would expose them to greater-than-minimal risk but also hold the prospect of direct benefit.
In “Ethics of International Research: What Does Responsiveness Mean?” Christine Grady explains how developing countries are vulnerable to exploitation by researchers and explores what “responsiveness” to the needs of those populations might entail.
The author argues that long-term trends point to a future for physician assistants and nurse practitioners as the principal front-line deliverers of primary care, with physicians focusing on managerial duties and specialty care.
Susanne Sheehy, BM BCh, MRCP, DTM&H and Joel Meyer, BM BCh, MRCP
The decline in numbers of healthy volunteers who participate in clinical trials has the potential to become a key rate-limiting factor in vaccine development.
Transgender people planning a medical transition face decisions about family planning, fertility preservation, and how to access gender-affirming treatment.
AMA J Ethics. 2016;18(11):1119-1125. doi:
10.1001/journalofethics.2016.18.11.pfor2-1611.