Specific advocate guidelines are needed for the protection of children in state custody who are potential research subjects in trials that would expose them to greater-than-minimal risk but also hold the prospect of direct benefit.
In “Ethics of International Research: What Does Responsiveness Mean?” Christine Grady explains how developing countries are vulnerable to exploitation by researchers and explores what “responsiveness” to the needs of those populations might entail.
Melissa Weddle, MD, MPH and Patricia K. Kokotailo, MD, MPH
Physicians should honor confidentiality whenever possible when screening and treating adolescents for sensitive health conditions such as substance abuse.