Weight loss is not a safe, effective, or permanent method of health promotion, and pharmacotherapeutical approaches pose specific risks to adolescents.
AMA J Ethics. 2023;25(7):E478-495. doi:
10.1001/amajethics.2023.478.
Specific advocate guidelines are needed for the protection of children in state custody who are potential research subjects in trials that would expose them to greater-than-minimal risk but also hold the prospect of direct benefit.