The Declaration of Helsinki was recently revised to require that the control arm of a trial use the current standard of care, even if that standard is not generally available in developing nations where the research is being conducted.
Dr Brady J. Heward joins Ethics Talk to discuss his article, coauthored with Drs Amy M. Yule and Peter R. Jackson: “How Should Harm Reduction Strategies Differ for Adolescents and Adults?”
Those conducting Western-style clinical trial research in developing countries must consider the manner in which ethical principals are implemented within local standards of care.