Advance directives, substituted judgment, and the best-interest standard all have limitations that constrain their usefulness in making medical decisions for patients who cannot choose for themselves.
Does a surgeon’s complication rate in a randomized controlled trial constitute a “significant new finding” that must be reported to patients during the consent process?
Tom Alsaigh, MD, Laura Nicholson, MD, PhD, and Eric Topol, MD
Clinicians should have a working understanding of gene editing, controversy surrounding its use, and its far-reaching clinical and ethical implications.
AMA J Ethics. 2019;21(12):E1089-1097. doi:
10.1001/amajethics.2019.1089.
Despite drawbacks of immunosuppression and surgery, vascularized composite allotransplants can enhance lives of patients who meet candidacy criteria and are well supported.
AMA J Ethics. 2019;21(11):E968-973. doi:
10.1001/amajethics.2019.968.
Primary materials including interviews with some of the volunteer subjects provide information on the experiments into the pathogenic mechanism of yellow fever.