The differences between CBPR and traditional research have been enumerated, but how to overcome them is still up for discussion, collaboration with community members is advocated, and examples are given.

By failing to follow informed consent protocols and regulations, a researcher engaging in CBPR may inflict permanent harm on the participating community and chill future research among disadvantaged populations.

The AMA Code of Medical Ethics' opinion on international research.

Guidelines for ethical research can inform the creation of standards for ethical international health partnerships.

The traditional triple threat model of academic physician careers can help global health researchers balance research commitments and the duty to care.

The University of Washington Pediatric Residency Program Experience in Global Health and Community Health and Advocacy embodies essential principles of successful short-term rotations from academic medical centers to resource-limited countries.

There are advantages and objections to conducting clinical trials in middle-income nations and possible approaches to overcoming the objections.

Primary materials including interviews with some of the volunteer subjects provide information on the experiments into the pathogenic mechanism of yellow fever.

The question that comes to mind when one considers the risks of a clinical trial is, “Why would anyone agree to participate?” Interviews with trial volunteers and their family members make clear that often it is the appeal of discovering something new and unknown.