AMA Journal of Ethics^®

Empathic communication skills help motivate understanding of safety, significance of harms, impact on succeeding generations, and social consequences.

Dr Sean C. McConnell provides an introduction to gene editing, and Scott J. Schweikart discusses what prudent governance requires.

Gene editing reminds professionals and the public that this technology’s reach goes beyond treating somatic disease to germline consequences yet unknown.

Transnational monitoring efforts should focus on safety, defining standard of care, and promoting just access to innovation.

In art, authenticity tends to be perceived in proximity to an artist’s original intention, and it can help guide future research in germline editing.

International debate about human genome editing governance has undergone a paradigm shift and suggests that inclusive public deliberation is still important.

Clinically and ethically relevant questions are related to patient safety, therapeutic efficacy, equitable access, and global governance over humanity’s genetic legacy.

Should couples undergoing IVF be allowed to request sex selection for nonmedical so-called family balancing?

Decisions about whether to pursue IVF for savior siblings are difficult to make when probable success rates differ by clinic and evidence is lacking.

Most discussion about using prenatal interventions to choose traits of children involves selecting traits that will contribute to intelligence, athleticism or strength, resistance to disease, and longevity, outcomes many of us would find desirable for ourselves.