Culturally appropriate responsiveness to mental illnesses is critical to mitigating local persons’ distrust of international clinicians.

Responding to patients violating US health commerce regulations can be critical when they buy and use unproven interventions.

Empathic communication skills help motivate understanding of safety, significance of harms, impact on succeeding generations, and social consequences.

Transnational monitoring efforts should focus on safety, defining standard of care, and promoting just access to innovation.

Success depends on strong support, rehabilitation, adherence, and social integration.

Counseling a patient about reconstructive surgery for a traumatic and disfiguring injury requires special consideration.

Clinician-researchers deeply invested in data gathering are still obliged to respect a patient-subject’s right to stop being in research.

Rather than relying on decision aids, values-based approaches to decision making illuminate a plurality of possible right actions.

Decision aids could help clinicians know when to request ethics consultation or re-evaluate blood product usage in a specific patient care situation.

Regulations’ negative influence on patient-physician relationships can be mitigated by innovation in decision science.