Because transplantation for methylmalonic acidaemia prioritizes quality of life over long-term outcomes, justice and utility must be considered.

Equal access is a goal even when patients present with taboo illnesses. But, the date of a patient’s last drink still matters.

Fostering transgender patients’ sense of agency should be a clinical and ethical priority.

Organ allocation models that maximize the collective benefit of an organ rely on subjective criteria and might have unintended practical consequences.

Recent advances in UTx suggest it is on a trajectory toward becoming an accepted clinical practice to treat absolute uterine factor infertility.

Given organ scarcity, transplantation programs state that patient promises of compliance cannot be taken at face value, excluding candidates who are deemed untrustworthy.

Transplant physicians must respect indecisive patients’ autonomy while continuing to educate them during their progress towards transplantation.

Despite clear donor consent, health professionals must communicate clearly about death to family members to avoid confusion.

Tension between realistic goals and unrealistic views about how to achieve them is compounded when patients are eager to revise a prior surgeon’s gender-affirming procedure.

Success in uterus transplantation among ciswomen suggests that transwomen and some transmen will also likely have interest in this intervention.