Targeted dosing to treat pediatric inflammatory bowel disease is challenging because dosing guidelines are based on data gathered from adult subjects of clinical trials. Patients’ families and health care organizations also incur high costs and must try to balance potential benefits against risks of ongoing monitoring.
AMA J Ethics. 2018;20(9):E841-848. doi:
10.1001/amajethics.2018.841.
Dania Pagarkar joins Ethics Talk to discuss her article, coauthored with Drs Erin Harrop and Lisa Erlanger: “How Should We Approach Body Size Diversity in Clinical Trials?”
Jonathan S. Towner, PhD, Luke Nyakarahuka, PhD, MPH, BVM, and Patrick Atimnedi, BVM
Marburg virus is carried by the Egyptian rousette bat, a common cave-dwelling fruit bat endemic to sub-Saharan Africa, where populations can exceed 50 000.
AMA J Ethics. 2024;26(2):E109-115. doi:
10.1001/amajethics.2024.109.
Gregory C. Gray, MD, MPH, Laura A. Pulscher, PhD, MSc, and Hisham O. Alsharif, MBBS
Since the 1990s, multiple infectious diseases have “spilled over” from nonhuman animals to infect humans and cause significant global morbidity and mortality.
AMA J Ethics. 2024;26(2):E122-131. doi:
10.1001/amajethics.2024.122.
Joelle I. Rosser, MD, MS, Orion X. Lavery, Rebecca C. Christofferson, PhD, MApSt, Juma Nasoro, Francis M. Mutuku, PhD, and A. Desiree LaBeaud, MD, MS
Organizations’ architecture and communities’ waste stream designs situate how well industrial hygiene practices support or undermine individuals’ and communities’ pathogenic vulnerability.
AMA J Ethics. 2024;26(2):E132-141. doi:
10.1001/amajethics.2024.132.
Given full information about the risks of long-term opioid therapy, patients often see the value of exploring other options rather than thinking their physicians are reluctant to prescribe narcotics for fear of litigation or regulatory action.
AMA J Ethics. 2015;17(3):202-208. doi:
10.1001/journalofethics.2015.17.3.ecas1-1503.