Financial relationships are common, and ethical questions rightly emerge about how conflicts of interest compromise investigators’ approaches to research.
AMA J Ethics. 2021;23(9):E685-691. doi:
10.1001/amajethics.2021.685.
Clinical equipoise—the idea that the community of medical experts is uncertain about the relative therapeutic merits of the arms of a clinical trial at its outset—mitigates physicians’ responsibility for patients’ poor outcomes when patients are assigned to the control arm or are harmed by an investigational agent.
AMA J Ethics. 2015;17(12):1108-1115. doi:
10.1001/journalofethics.2015.17.12.ecas1-1512.
Framing discussions of ALS around the disease rather than the psychologically complex person with the disease focuses attention on symptoms and imagined outcomes rather than patients’ coping strategies and quality of life.
AMA J Ethics. 2015;17(6):530-534. doi:
10.1001/journalofethics.2015.17.6.nlit2-1506.