Specific advocate guidelines are needed for the protection of children in state custody who are potential research subjects in trials that would expose them to greater-than-minimal risk but also hold the prospect of direct benefit.
Sheldon Zink, PhD, Rachel Zeehandelaar, and Stacey Wertlieb, MBe
The benefits of the international presumed-consent policy are presented as a solution to the United States' current shortage of organs available for transplantation.
Alcoholics should not be subject to deprioritization on a liver transplant waiting list if the belief is held that alcoholism is a disease and not an issue of moral failure for which the patient should be blamed.
Dr David DeGrazia joins Ethics Talk to discuss why the “3 R’s” of nonhuman animal research might not be sufficient to promote good science, ethics, and nonhuman animal welfare.
Historically, most discussions about nonhuman animal experimentation consider what has become known as the 3 R’s: refinement, reduction, and replacement.
AMA J Ethics. 2024;26(9):E701-708. doi:
10.1001/amajethics.2024.701.
Ethically justifying human-centered research with only nonhuman animals as subjects likely requires that the research’s benefits to humans must, at least, outweigh harms suffered by the nonhuman animals.
AMA J Ethics. 2024;26(9):E673-678. doi:
10.1001/amajethics.2024.673.
Theodore E. Schall, PhD, MSW, MBE, Kaitlyn Jaffe, PhD, and Jacob D. Moses, PhD
Clinicians should know how randomized controlled trials can and cannot contribute to advancing health equity for transgender and gender diverse people.
AMA J Ethics. 2024;26(9):E684-689. doi:
10.1001/amajethics.2024.684.