Primary materials including interviews with some of the volunteer subjects provide information on the experiments into the pathogenic mechanism of yellow fever.
A review of a landmark case that determined why and under what circumstances antipsychotic medications can be administered to incarcerated patients with mental illness against their will.
Clinical and psychosocial considerations influence how oncologists approach discussing sperm banking with adolescent patients who are about to undergo chemotherapy and with the parents of those patients.
A close study of a literary memoir can help resident physicians understand the complex, inextricable relationship between a patient’s autonomy and his vulnerability.
Basic information about the two principal instruments used for assessing patients' decision-making competence and learn why both fall short of reliable, objective assessment.
Specific advocate guidelines are needed for the protection of children in state custody who are potential research subjects in trials that would expose them to greater-than-minimal risk but also hold the prospect of direct benefit.
Physicians’ ethical obligations to disclose conflicts of interest to patients and to obtain their informed consent for treatment are particularly critical when proposed treatments are experimental.
Clinical trials for the blood substitute PolyHeme exposed the possibility for ambiguous interpretation of the FDA’s waiver of informed consent for emergency research.