The alarm generated by the AIDS epidemic left civil liberties proponents fearful that traditional public health responses might be imposed on newly susceptible or infected populations.

Heightened privacy and confidentiality stakes generate unique anonymity and nondisclosure policies and practices for HIV.

Deception’s justifiability might depend on clinicians’ commitment to solidarity and awareness of social determinants of patients’ vulnerability to HIV infection.

Patient-centered care means offering potentially beneficial interventions while avoiding retraumatizing a patient.

The AMA Code of Medical Ethics offers guidance on HIV screening that expresses respect for patient autonomy while protecting public health.

Long-acting injectables powerfully augment HIV care, but broad acceptance and uptake could be compromised by what we know about experiences with antipsychotics.

Ending AIDS requires normalizing justice-based approaches to HIV care and acknowledging how power dynamics shape popular narratives and practices.

Merits and drawbacks of U = U messaging are ethically and clinically complex, and drawbacks could harm patients in whom viral suppression is hard to achieve.

Global transformation demanded by COVID-19 prompts consideration of how prior epidemics have shaped our cultural and sociological understandings of health care experiences.