Physicians are obligated to inform patients involved in a clinical trial that there is a chance of receiving a placebo, which can result in a deterioration of a medical condition.
Research ethics should be included in the medical school curriculum so students and residents can fully understand the ethical implications of medical research.
The Declaration of Helsinki was recently revised to require that the control arm of a trial use the current standard of care, even if that standard is not generally available in developing nations where the research is being conducted.
Those conducting Western-style clinical trial research in developing countries must consider the manner in which ethical principals are implemented within local standards of care.
Adrienne W. Henize, JD and Andrew F. Beck, MD, MPH
Data on certain chronic conditions’ prevalence, incidence of potentially preventable morbidity, and health-harming legal factors influence approaches to care.
AMA J Ethics. 2024;26(8):E648-654. doi:
10.1001/amajethics.2024.648.