Therapeutic misconception—a false belief that individuals will benefit from participating in research—can bias informed consent. Ethics consultants can help by engaging participants’ and researchers’ understandings of risks and benefits and by asking good questions about the influences of researchers’ enthusiasm.

Clinician-researchers deeply invested in data gathering are still obliged to respect a patient-subject’s right to stop being in research.

Shared decision making in research informed consent conversations is complex due to diverse and potentially divergent interests of investigators and patient-subjects.

Drs Katrina Bramstedt and Ana Iltis discuss the development of QoL assessment tools to help patient-subjects considering reconstructive transplantation.

Helping patients mitigate their risk of chronic disease is key, but dietary supplements are risky.

Children with micronutrient deficiency might need supplementation, sometimes in irregularly high doses.

Consumption of over-the-counter vitamins, minerals, and herbals is widespread, but clinicians lack critical information about their use.

Label analysis is key to educating patients about risks of vitamin A-containing supplements.

Increase in dietary supplement use in the United States suggests a great need for clinicians to be aware of the range of their quality parameters.

Dietary supplements can have side effects; interact with medications, food, or other supplements; or be unsafe.