Decision aids could help clinicians know when to request ethics consultation or re-evaluate blood product usage in a specific patient care situation.

Legal inconsistencies and variation in end-of-life options generate disparities in care for unrepresented patients.

African cancer research is embedded in underresourced health care infrastructures, illuminating ethical questions about benefit sharing and governance.

IRBs must report human subject research protocol deviations and university leadership might also need to motivate compliance with federal regulations.

Key policy changes would better situate clinicians to prescribe care in ways that are ethical, safe, and effective.

Systematic analysis of extant research ethics guidance is needed for conflict-affected countries and UN agencies.

Emergency research that requires exception from informed consent presents challenges in defining and reaching the at-risk community.

The AAP’s guidelines on lipid screening for children raise concerns about the fundamental purpose of prevention and its role in balancing individual autonomy with the benefits of society at large.