Physicians are cautioned that the two obstacles to reforming post-marketing clinical trials are the FDA's reluctance to revisit past approvals and its inability to enforce pharmaceutical companies' commitment to conduct Phase IV trials.
A physician outlines the RAND Health Insurance Experiment and its conclusion that the deductible feature of consumer-directed health plans can reduce health care spending significantly.
Consumer-directed health plans will result in a more responsive and sustainable health care system in which patients will take more responsibility for management of their chronic conditions.
Drs Lynne Fehrenbacher and Leah Leonard-Kandarapally join Ethics Talk to discuss key roles of infectious disease pharmacists in antimicrobial stewardship.
Parents' ability to make medical decisions for their children can be limited by state law if it is determined that the child's best interest is not being met.
A physician defends her position that children should only participate in clinical trials when they have child assent and the parents also have been educated about the purpose of the research when there is no direct benefit to the child.
Two physicians offer commentaries about the use of prenatal predictive testing for a late-onset disease like Huntington's and question whether the pregnant woman should ultimately have the decisional autonomy to determine the quality of life of the unborn child.