Drs Michael Young, Robert Regenhardt, and Leonard Sokol join Ethics Talk to discuss their article, coauthored with Dr Thabele Leslie-Mazwi: "When Should Neuroendovascular Care for Patients With Acute Stroke Be Palliative?"

Lack of ethical, legal, and clinical consensus about best practice sometimes combines with a poor clinical evidence base.

Some technological and policy strategies for increasing organ supplies are ethically and legally proven to work. Consider best next steps for global education efforts to raise organ donation awareness.

Because transplantation for methylmalonic acidaemia prioritizes quality of life over long-term outcomes, justice and utility must be considered.

Equal access is a goal even when patients present with taboo illnesses. But, the date of a patient’s last drink still matters.

Fostering transgender patients’ sense of agency should be a clinical and ethical priority.

For some patients whose survival is extended by disease-modifying interventions, little guidance about clinical and ethical complexities exist.

Guidance about sedation to unconsciousness and medically ineffective interventions can be applied to surgical palliation.

Standards for posttransplant graft/survival rates do not reward transplant centers for performing riskier transplants to increase population benefit.