Clinical trials for the blood substitute PolyHeme exposed the possibility for ambiguous interpretation of the FDA’s waiver of informed consent for emergency research.
In “Ethics of International Research: What Does Responsiveness Mean?” Christine Grady explains how developing countries are vulnerable to exploitation by researchers and explores what “responsiveness” to the needs of those populations might entail.
A physician defends her position that children should only participate in clinical trials when they have child assent and the parents also have been educated about the purpose of the research when there is no direct benefit to the child.
Sheldon Zink, PhD, Rachel Zeehandelaar, and Stacey Wertlieb, MBe
The benefits of the international presumed-consent policy are presented as a solution to the United States' current shortage of organs available for transplantation.
The genetic engineering of organ-donor animals to decrease the risk of human immune system rejection poses ethical and psychological challenges to the long-held boundary between humans and other animal species.
An ethical case explores a lawsuit against Fred Hutchinson Cancer Center of Seattle by patients who claimed they were not told of the full risks associated with a clinical trial they participated in.