The early diagnosis of Alzheimer disease is a boon in that it enables advance planning, but that planning process can engender conflict between respect for future-oriented autonomy and future welfare.
A consensus has emerged that the paternalism behind use of the provocative saline infusion test for nonepileptic seizures cannot be justified because the harms to the patient, the physician, and their relationship exceed the benefits.
Primary materials including interviews with some of the volunteer subjects provide information on the experiments into the pathogenic mechanism of yellow fever.
The author explains why ear reconstruction is not enhancement surgery, and argues that the American system of health care reimbursement sometimes makes advocating for reimbursement part of treatment.
Specific advocate guidelines are needed for the protection of children in state custody who are potential research subjects in trials that would expose them to greater-than-minimal risk but also hold the prospect of direct benefit.
In “Ethics of International Research: What Does Responsiveness Mean?” Christine Grady explains how developing countries are vulnerable to exploitation by researchers and explores what “responsiveness” to the needs of those populations might entail.
Clinical trials for the blood substitute PolyHeme exposed the possibility for ambiguous interpretation of the FDA’s waiver of informed consent for emergency research.