Elderly persons should not be excluded from participation in clinical trials for cardiovascular drugs since that population comprises the largest number of patients with cardiovascular disease.
The Oxford Centre for Evidence-Based Medicine provides a scale for stratifying evidence from strongest to weakest on the basis of susceptibility to bias and the quality of study design.
The default principle—that someone is free to do what he or she desires in the absence of a compelling reason why he or she should not—may make it possible to resolve ethical disputes without recourse to a particular moral framework.
AMA J Ethics. 2015;17(4):289-296. doi:
10.1001/journalofethics.2015.17.4.spec1-1504.
Because many complementary and alternative medicine therapies for autism are based on misguided notions of its cause and lack support from scientifically sound studies, physicians should steer parents away from these practices and toward safe, effective, and evidence-based interventions.
AMA J Ethics. 2015;17(4):375-380. doi:
10.1001/journalofethics.2015.17.4.sect2-1504
The American College of Physicians and the Federation of State Medical Boards’ guidelines for online medical professionalism apply existing norms of communication and confidentiality to new settings but will need to be modified in light of technological advances and unanswered questions.
AMA J Ethics. 2015;17(5):441-447. doi:
10.1001/journalofethics.2015.17.5.nlit1-1505.
Christina Krudy, MD and Kavita Shah Arora, MD, MBE
Antenatal corticosteroids aren’t as effective in reducing neonatal mortality in low-income as high-income regions due to cultural and health care differences.
AMA J Ethics. 2018;20(3):261-268. doi:
10.1001/journalofethics.2018.20.3.stas1-1803.
Physicians should not only avoid forming personal relationships with drug reps but must also acquire and apply numeracy skills and information management strategies to critically evaluating drug reps’ information.
AMA J Ethics. 2015;17(8):729-733. doi:
10.1001/journalofethics.2015.17.8.ecas1-1508.
J. Brian Szender, MD, MS and Shashikant B. Lele, MD
The estimated reduction in risk of ovarian cancer for any woman undergoing opportunistic removal of the Fallopian tubes is up to 50 percent, but whether removal is more beneficial than ligation has not been established.
AMA J Ethics. 2015;17(9):843-848. doi:
10.1001/journalofethics.2015.17.9.stas1-1509.
Diethylstilbestrol (DES) was widely used in the 1940s to 1960s to prevent pregnancy loss but was later found to be associated with adverse health effects in exposed offspring, underscoring the need for careful evaluation of new therapies.
AMA J Ethics. 2015;17(9):865-870. doi:
10.1001/journalofethics.2015.17.9.mhst1-1509.