Clinical equipoise—the idea that the community of medical experts is uncertain about the relative therapeutic merits of the arms of a clinical trial at its outset—mitigates physicians’ responsibility for patients’ poor outcomes when patients are assigned to the control arm or are harmed by an investigational agent.
AMA J Ethics. 2015;17(12):1108-1115. doi:
10.1001/journalofethics.2015.17.12.ecas1-1512.
Meera Balasubramaniam, MD, MPH and Yesne Alici, MD
A 15-year-old advance directive made when the patient was in much better health and not updated can bring more confusion than clarity to the decision-making process.
A 15-year-old advance directive made when the patient was in much better health and not updated can bring more confusion than clarity to the decision-making process.
Conducting community-based research in the community where one resides demands careful planning, sensitivity to community members’ privacy, and a strong commitment to full and respectful communication.
Laura N. Gitlin, PhD and Nancy A. Hodgson, PhD, RN
As a matter of medical ethics, physicians must address the health care needs of and be advocates for family caregivers of their patients with dementia.
AMA J Ethics. 2016;18(12):1171-1181. doi:
10.1001/journalofethics.2016.18.12.ecas1-1612.
When deciding whether to offer deep brain stimulation earlier than usual for Parkinson disease, it is important to consider not only the patient’s autonomy but also the validity of the evidence and concepts of harm that are being used to form practice policies.
When a seriously ill mature minor and his parent disagree about his receiving an experimental intervention, who should decide what treatment he will receive?
Elizabeth Lee Daugherty, MD, MPH and Douglas B. White, MD, MA
Opportunities to advance scientific knowledge may arise during humanitarian crises, but their presence does not justify suspension of the ethical foundations governing human subjects research.
Patricia D. Quigley, MD and Megan A. Moreno, MD, MSEd, MPH
Maintaining an adolescent’s confidentiality while answering his or her parents’ questions about their child’s change in mood and behavior can be challenging.