Safeguards are urgently needed for assessments of what constitutes appropriate care for unaccompanied minors in US detention facilities.

Risks of off-label medication to treat aggression should be balanced with consequences of not responding to social factors.

Those who care for adolescents must advocate for timely disclosure of HIV diagnosis since the negative effects of late disclosure include social isolation, anxiety, loss of trust, and depression.

Physicians who treat children with Down's syndrome should ensure that their parents fully understand the children's capabilities and long-term prognosis and counsel them on the appropriate actions to take regarding their children's care.

Recent increases in adolescent mortality from overdose have outpaced increases in mortality in members of the general population.

Dr Brady J. Heward joins Ethics Talk to discuss his article, coauthored with Drs Amy M. Yule and Peter R. Jackson: “How Should Harm Reduction Strategies Differ for Adolescents and Adults?”