AMA Journal of Ethics theme editor Subha Perni, MD, a recent graduate of the Columbia University College of Physicians and Surgeons, interviewed Elizabeth Epstein, PhD, RN, about strategies for understanding and address moral distress in clinical settings.

In clinical settings, chaplains are key communicators who help mediate between patients, families, and the medical team. This month on Ethics Talk, we explore how chaplains help patients and families articulate their goals and navigate logistical and emotional challenges that arise in the hospital.

Drs Pringl Miller, Preeti John, and Sabha Ganai join Ethics Talk to discuss their article: “How Should Surgical Palliative Success Be Defined?”

Dr Olivia Kates talks about appropriate use of antibiotics during the COVID-19 pandemic.

Prof Ana Santos Rutschman talks about the impact of intellectual property regimes on domestic and global responses to the COVID-19 pandemic.

Dr Steven Goodman talks about the ethical and scientific implications of breaking the blind of placebo-controlled COVID-19 vaccine trials.

Dr Arthur Caplan talks about ethical issues surrounding the development, production, and use of potential SARS-CoV-2 vaccine.

Dr Caleb Alexander examines the US Food and Drug Administration's controversial decision to approve aducanumab for the treatment of Alzheimer's Disease.

Drs Stefano Bertozzi and Jeffrey Mackie-Mason talk about business models of scientific publishing that advance biomedical knowledge and discovery.

When the patient delivers a low-birth-weight infant that requires extensive time in the neonatal intensive, should she be held responsible? Where do we draw the line? More importantly, on what basis do we draw the line?