The Holocaust and the racial hygiene doctrine that helped rationalize it still overshadow contemporary debates about using gene editing for disease prevention.

Heightened privacy and confidentiality stakes generate unique anonymity and nondisclosure policies and practices for HIV.

Deception’s justifiability might depend on clinicians’ commitment to solidarity and awareness of social determinants of patients’ vulnerability to HIV infection.

Patient-centered care means offering potentially beneficial interventions while avoiding retraumatizing a patient.

The AMA Code of Medical Ethics offers guidance on HIV screening that expresses respect for patient autonomy while protecting public health.

Merits and drawbacks of U = U messaging are ethically and clinically complex, and drawbacks could harm patients in whom viral suppression is hard to achieve.

Drs Oliva Kates and Monica Gandhi join Ethics Talk to discuss equity and public health messaging in ending the HIV epidemic.

Fostering transgender patients’ sense of agency should be a clinical and ethical priority.

Law doesn’t always adequately address unauthorized uses of individuals’ DNA. Ethics can help establish legal privacy protections that work.

Prognostic uncertainty about risk creates demand for ongoing communication and facilitated reflection about goals and values.