Risk managers can help patient-subjects and clinician-researchers make informed novel device implantation decisions in the absence of preclinical trial data.

Neurophysiological sequelae of childhood trauma can express later in the lives of patients experiencing homelessness, especially during informed consent.

A capabilities model helps reframe health care as shared between a clinical team and some of our most vulnerable patients.

Improving candidate evaluation and informed consent is key to motivating authenticity, not just voluntariness.

Clinical decision supports create ethically complex risks and need to align patients’ and caregivers’ professed values.

Two commentaries respond to a case about apnea testing to confirm death by neurologic criteria.

Two pediatric cases highlight risks of prolonging anesthetic exposure for training purposes and prompt questions about influences of surgical training on outcomes.

Using alternative anesthesia techniques requires collaborative decision making that expresses a patient’s best interest.

Which factors should be part of standard required reconsideration discussions?

Current policy requires separate informed consent for some Public Health Service increased-risk donors, and this can make shared decision making harder.