Dr Sean C. McConnell provides an introduction to gene editing, and Scott J. Schweikart discusses what prudent governance requires.

This month, AMA Journal of Ethics theme editor Jacquelyn Nestor, a fifth-year MD/PhD student at Hofstra-Northwell School of Medicine, interviewed Allen Buchanan, PhD, about how we can safely explore cutting-edge biomedical enhancements.

Prof Ana Santos Rutschman talks about the impact of intellectual property regimes on domestic and global responses to the COVID-19 pandemic.

Dr Steven Goodman talks about the ethical and scientific implications of breaking the blind of placebo-controlled COVID-19 vaccine trials.

Dr Arthur Caplan talks about ethical issues surrounding the development, production, and use of potential SARS-CoV-2 vaccine.

Dr Caleb Alexander examines the US Food and Drug Administration's controversial decision to approve aducanumab for the treatment of Alzheimer's Disease.

Drs Stefano Bertozzi and Jeffrey Mackie-Mason talk about business models of scientific publishing that advance biomedical knowledge and discovery.

Gene editing to enhance humans’ adaptability to climate change should consider safety, harm to be averted, succeeding generations, and social consequences.

Disparities in children’s mental health care could be addressed through expansion of school-based programs via passage of the Mental Health in Schools Act.

Due to insurance company regulations, current restrictions on access to mental health care prevent many from obtaining needed care.