Dr Travis Rieder discusses his own experiences with opioids and the ethical challenges of “legacy patients,” and Dr Stephanie Zaza, president of the American College of Preventive Medicine, discusses the future of opioid research priorities.

Dr Jim Withers and Dave Lettrich join Ethics talk to discuss how street outreach programs help mitigate harms of drug use among people experiencing homelessness.

This month on Ethics Talk, Dr Sheryl Fleisch discusses strategies for delivering health services to people experiencing homelessness, including street psychiatry.

Dr Arthur Caplan talks about hesitancy among US health care workers to take COVID-19 vaccines authorized by the FDA for emergency use.

Dr Arthur Caplan talks about ethical issues surrounding the development, production, and use of potential SARS-CoV-2 vaccine.

Prof Debbie Kaminer talks about vaccine mandates and other policy solutions to promote herd immunity against COVID-19.

An educational initiative is described in which medical and bioethics students observe health care in an urban jail for two days and reflect on their learning.

This commentary on a case considers how clinicians can help nonbinary patients minimize potential harms of psychedelics.

Severe withdrawal, risk of patient-initiated discharge, and some inpatients’ uses of substances prompt questions considered in this commentary.

Reconsider regulatory and clinical frameworks for prescribing long-term opioid therapy for pain and prescribing opioids to treat OUD.