Jonathan Alhalel, Nicolás Francone, Sharon Post, Catherine A. O’Brian, PhD, and Melissa A. Simon, MD, MPH
Underrepresentation of individuals with limited English proficiency who speak Spanish is ongoing in phase 3 biomedical clinical trials and exacerbates health inequity.
AMA J Ethics. 2022;24(4):E319-325. doi:
10.1001/amajethics.2022.319.
Targeted dosing to treat pediatric inflammatory bowel disease is challenging because dosing guidelines are based on data gathered from adult subjects of clinical trials. Patients’ families and health care organizations also incur high costs and must try to balance potential benefits against risks of ongoing monitoring.
AMA J Ethics. 2018;20(9):E841-848. doi:
10.1001/amajethics.2018.841.
Dr Aysha Akhtar joins Ethics Talk to discuss her article, coauthored with Mikalah Singer, “With What Should We Replace Nonhuman Animals in Biomedical Research Protocols?”
Erin Sharoni joins Ethics Talk to discuss her article: “Which Concepts Are Key to Transitioning From Nonhuman Animal Models to Engineered Microphysiological Systems in Biomedical Research?”
Dr David DeGrazia joins Ethics Talk to discuss why the “3 R’s” of nonhuman animal research might not be sufficient to promote good science, ethics, and nonhuman animal welfare.