When patients are unable to express their wishes and do not have surrogates or advance directives, which and whose values should inform decision making for them? We discuss ethical complexities of caring for unrepresented patients.

Dr Laura Guidry-Grimes helps us consider whether and which decisions can be shared with people experiencing mental illnesses.

Ari Ne’eman joins Ethics Talk to discuss his article, When Disability is Defined by Behavior, Outcome Measures Should Not promote “Passing”.

AMA Journal of Ethics editor Audiey Kao, MD, PhD, interviewed Richard Pan, MD, MPH, about how, as a physician and legislator, he seeks to protect public health in light of recurrent outbreaks of vaccine-preventable infectious diseases.

AMA Journal of Ethics theme editor Emily Johnson, a fourth-year medical student at the University of Colorado School of Medicine, interviewed Susan Mizner, JD, about some merits, drawbacks, and alternatives to guardianship.

Eva V. Regel joins Ethics Talk to discuss her article: “How Should Clinicians Help Homeless Trauma Survivors Make Irreversible Surgical Care Decisions?”

Dr Arthur Caplan talks about hesitancy among US health care workers to take COVID-19 vaccines authorized by the FDA for emergency use.

Dr Arthur Caplan talks about ethical issues surrounding the development, production, and use of potential SARS-CoV-2 vaccine.

Prof Debbie Kaminer talks about vaccine mandates and other policy solutions to promote herd immunity against COVID-19.