Antibiotics can be compared to other forms of “tragedy of the commons,” whereby a common good (effective treatment of infections) is jeopardized by individual consumption and lack of stewardship.
AMA J Ethics. 2024; 26(5):E418-428. doi:
10.1001/amajethics.2024.418.
Primary materials including interviews with some of the volunteer subjects provide information on the experiments into the pathogenic mechanism of yellow fever.
The bias for publishing positive clinical-research results can cause physicians to question journal articles as dependable sources of product information.
Institutional review boards (IRBs) have the responsibility to ensure the protection of human-research subjects and are legally liable if they fail to do so.