Dr Sean C. McConnell provides an introduction to gene editing, and Scott J. Schweikart discusses what prudent governance requires.

Kelly Leonard, executive director of insights and applied improvisation at Second City Works, relates how improvisation can help clinicians build relationships with patients and improve their outcomes.

This month, AMA Journal of Ethics theme editor Jacquelyn Nestor, a fifth-year MD/PhD student at Hofstra-Northwell School of Medicine, interviewed Allen Buchanan, PhD, about how we can safely explore cutting-edge biomedical enhancements.

Dr Olivia Kates talks about appropriate use of antibiotics during the COVID-19 pandemic.

Dr Arthur Caplan talks about ethical issues surrounding the development, production, and use of potential SARS-CoV-2 vaccine.

Prof Debbie Kaminer talks about vaccine mandates and other policy solutions to promote herd immunity against COVID-19.

Gene editing to enhance humans’ adaptability to climate change should consider safety, harm to be averted, succeeding generations, and social consequences.

Physicians should be aware of the level of emotional distress and suffering that a patient is experiencing as a result of his or her illness and incorporate that into the patient's treatment plan.

Physicians should go beyond basic medical diagnosis and treatment to offer support to families about the gamut of social and emotional issues that are involved with caring for a severely disabled child.

Physicians need to manage expectations and clearly explain the prognosis of ICU patients to their families, particularly when the outcome is a negative one.