Dr Sean C. McConnell provides an introduction to gene editing, and Scott J. Schweikart discusses what prudent governance requires.

This month, AMA Journal of Ethics theme editor Jacquelyn Nestor, a fifth-year MD/PhD student at Hofstra-Northwell School of Medicine, interviewed Allen Buchanan, PhD, about how we can safely explore cutting-edge biomedical enhancements.

Dr Olivia Kates talks about appropriate use of antibiotics during the COVID-19 pandemic.

Prof Ana Santos Rutschman talks about the impact of intellectual property regimes on domestic and global responses to the COVID-19 pandemic.

Dr Steven Goodman talks about the ethical and scientific implications of breaking the blind of placebo-controlled COVID-19 vaccine trials.

Dr Arthur Caplan talks about ethical issues surrounding the development, production, and use of potential SARS-CoV-2 vaccine.

Dr Caleb Alexander examines the US Food and Drug Administration's controversial decision to approve aducanumab for the treatment of Alzheimer's Disease.

Drs Stefano Bertozzi and Jeffrey Mackie-Mason talk about business models of scientific publishing that advance biomedical knowledge and discovery.

Gene editing to enhance humans’ adaptability to climate change should consider safety, harm to be averted, succeeding generations, and social consequences.

Although parents may someday have the ability to enhance the complex physical and mental traits of their offspring, such genetic enhancements raise a number of difficult ethical questions.