AMA Journal of Ethics theme editor Emily Johnson, a fourth-year medical student at the University of Colorado School of Medicine, interviewed Susan Mizner, JD, about some merits, drawbacks, and alternatives to guardianship.

Personal genome analysis available online

Dr Olivia Kates talks about appropriate use of antibiotics during the COVID-19 pandemic.

There is a market for direct-to-consumer genetic testing and a need for better consumer information and more regulation of tests and testing laboratories.

Research questions must be answered to inform policy decisions about the hereditary diseases and conditions for which newborns should be tested.

The question of whether and how results from personal genetic testing will motivate behavioral changes in consumers has only begun to receive the research attention it richly deserves.

Elder self-neglect can be assessed with the Elder Self-Neglect Assessment (ESNA) and addressed by physicians’ partnering with patients to achieve common goals.

Physicians should provide women considering abortion after Down syndrome screening with unbiased information and not attempt to influence their decision.

A guardian’s request to sterilize a woman with intellectual disabilities is not ethically justifiable unless the woman assents and it is to her benefit.

Noninvasive prenatal testing arguably constitutes a form of eugenics in a social context in which certain reproductive outcomes are not valued.