Dr Sean C. McConnell provides an introduction to gene editing, and Scott J. Schweikart discusses what prudent governance requires.

AMA Journal of Ethics theme editor Terri Davis, a third-year MD student at West Virginia University School of Medicine, interviewed Ranit Mishori, MD, about how to respond to incidents of suspected human trafficking in health care settings.

Dr Ariane Lewis discusses how we can navigate uncertainty and ambiguity about brain death by understanding clinical criteria for brain death determination and how our approaches to death are culturally and socially situated.

Large precision health initiatives like the National Institutes of Health’s All of Us campaign raise important ethical questions about consent, privacy, and inclusivity. This month on Ethics Talk, we explore with Dr Katie Johansen Taber and Ysabel Duron strategies for protecting participants and ensuring that diverse communities are represented.

Drs Oliva Kates and Monica Gandhi join Ethics Talk to discuss equity and public health messaging in ending the HIV epidemic.

Which distinctions between minimally conscious states and vegetative states should clinicians consider?

Physicians caring for trafficking victims should know about applicable criminal and human rights law and mandatory reporting requirements.

Public health surveillance for infectious disease provides a model for a mandatory reporting policy for human trafficking, which poses risks for survivors.

The alarm generated by the AIDS epidemic left civil liberties proponents fearful that traditional public health responses might be imposed on newly susceptible or infected populations.

Before new cases of HIV/AIDS will decline, more Americans must recognize that “it could happen to them.”