Dr Sean C. McConnell provides an introduction to gene editing, and Scott J. Schweikart discusses what prudent governance requires.

This month, AMA Journal of Ethics theme editor Jacquelyn Nestor, a fifth-year MD/PhD student at Hofstra-Northwell School of Medicine, interviewed Allen Buchanan, PhD, about how we can safely explore cutting-edge biomedical enhancements.

AMA Journal of Ethics theme editor Emily Johnson, a fourth-year medical student at the University of Colorado School of Medicine, interviewed Susan Mizner, JD, about some merits, drawbacks, and alternatives to guardianship.

Gene editing to enhance humans’ adaptability to climate change should consider safety, harm to be averted, succeeding generations, and social consequences.

Elder self-neglect can be assessed with the Elder Self-Neglect Assessment (ESNA) and addressed by physicians’ partnering with patients to achieve common goals.

A guardian’s request to sterilize a woman with intellectual disabilities is not ethically justifiable unless the woman assents and it is to her benefit.

The best interests of a pregnant psychotic patient can be served by determining her decision making capacity and using surrogate decision making if needed.

The American Medical Association Code of Medical Ethics’ opinions on physicians’ self-referral and physicians’ sale of health-related and non-health-related products from their offices.

A physician responds to a previous article about the differences between using a commercial laboratory and a smaller hospital or pathology group lab for dermatological tests.

A physician and a lawyer argue against a dermatology clinic switching from a small, reliable pathology lab to a large-scale pathology lab in order to receive volume discounts and increase profit.