In treating children with autism, physicians should focus on involving parents in a shared decision making partnership and seeking safe, evidence-based, and medically and cost-effective treatments.

The harms of communicating autism risk can be avoided by helping families to understand risk and to distinguish between poor and good sources of scientific information, which should take families’ interests into account.

N-of-1 trials bring the rigor of research to an individual patient's clinical benefit.

Prognostication means informing patients what the outcome of their illnesses and treatments are expected to be, based on the best available evidence. Prognosticating in a way that helps patients in decision making about treatment is difficult for physicians to do.

While next-generation genome sequencing can successfully guide cancer therapy, it can also reveal significant incidental findings that patients, families, and physicians may not be prepared to handle and may not want to know.

Shared decision making requires that physicians acknowledge their responsibility to the patient, their responsibility to be true to their own clinical judgment about the patient's best interest, their accountability to society, and the uncertainty of the evidence.

If wealth screening and patient care must be mixed, they would be safer and more effective if guided by a policy developed with input from physicians.

Virtue ethics can point the way toward an appropriate approach to communicating a diagnosis of nonepileptic seizures.

The early diagnosis of Alzheimer disease is a boon in that it enables advance planning, but that planning process can engender conflict between respect for future-oriented autonomy and future welfare.

The AMA Code of Medical Ethics' opinions on disclosing diagnoses to patients.