Dr Sean C. McConnell provides an introduction to gene editing, and Scott J. Schweikart discusses what prudent governance requires.

This month, AMA Journal of Ethics theme editor Jacquelyn Nestor, a fifth-year MD/PhD student at Hofstra-Northwell School of Medicine, interviewed Allen Buchanan, PhD, about how we can safely explore cutting-edge biomedical enhancements.

Dr Olivia Kates talks about appropriate use of antibiotics during the COVID-19 pandemic.

Dr Arthur Caplan talks about ethical issues surrounding the development, production, and use of potential SARS-CoV-2 vaccine.

Prof Debbie Kaminer talks about vaccine mandates and other policy solutions to promote herd immunity against COVID-19.

Gene editing to enhance humans’ adaptability to climate change should consider safety, harm to be averted, succeeding generations, and social consequences.

Rosemarie Garland-Thomson’s argument for disability as a sociocultural resource challenges the commonsense understanding of disability as a deficit.

Physicians need to educate patients about nutrition to counter the plethora of media images that promote poor dietary habits.

A digital record of place history and environmental context can provide a piece of clinically relevant information to help physicians understand what toxins patients may have been exposed to.

Although parents may someday have the ability to enhance the complex physical and mental traits of their offspring, such genetic enhancements raise a number of difficult ethical questions.