The first women’s movement in the mid-nineteenth century endorsed anesthesia during childbirth and some of the very patterns of obstetric practice that became anathema to the natural childbirth movement a century later.
AMA J Ethics. 2015;17(3):253-257. doi:
10.1001/journalofethics.2015.17.3.msoc1-1503.
Specific advocate guidelines are needed for the protection of children in state custody who are potential research subjects in trials that would expose them to greater-than-minimal risk but also hold the prospect of direct benefit.
An explanation of the legal origin of informed consent, the key court decisions in establishing the principle of consent to treatment, and the knowledge of risks and benefits necessary to “inform” the consent process adequately.
The ongoing anthrax vaccination case, Doe v Rumsfeld, tests whether the military can require participation in and punish refusal of a vaccination program while waiving informed consent.
The drug Neurontin is used as an example of why it is permissible for physicians to engage in off-label prescribing, but off-label marketing by pharmaceutical companies is prohibited by the FDA.