Burn care physicians must walk a fine line between providing individualized care and applying population-based quality metrics.

A number of resources currently devoted to neonatal intensive care may be better spent in prenatal care and prevention of preterm birth.

Overall utilization of the few biosimilars currently available to patients has been limited.

Two physicians examine the history of cancer drug pricing and the barriers to setting fair prices for life-saving cancer medications.

A physician argues that cost should not be a major consideration in a hospital's decision to provide palliative care services to patients.

In today's medical economy, cost effectiveness is becoming a bigger factor in developing standardized clinical practice guidelines.

A basic standard for error disclosure for physicians needs to be developed, which will enhance the patient-physician relationship.

Using data from comparative effectiveness studies to inform cost-effectiveness analyses or other economic evaluations would strengthen ethical policy making.

Many treatments are given to patients who have little to gain from them.

This process of developing EBM-based guidelines and applying them to clinical care highlights the tension between generating unbiased knowledge based on statistical aggregation and the application of this information to individual patients.