Dr David DeGrazia joins Ethics Talk to discuss why the “3 R’s” of nonhuman animal research might not be sufficient to promote good science, ethics, and nonhuman animal welfare.

Professor Richard L. Cupp Jr joins Ethics Talk to discuss his article: “How Might Corporations’ and Nonhuman Animals’ Personhood Compare Under the Fifth and Fourteenth Amendments?”

Erin Sharoni joins Ethics Talk to discuss her article: “Which Concepts Are Key to Transitioning From Nonhuman Animal Models to Engineered Microphysiological Systems in Biomedical Research?”

Laurie Sellars joins Ethics Talk to discuss her article, coauthored with Dr Jeff Sebo: “How Should Treatment of Animals Beyond the Lab Factor Into Institutional Review?”

Dr Aysha Akhtar joins Ethics Talk to discuss her article, coauthored with Mikalah Singer, “With What Should We Replace Nonhuman Animals in Biomedical Research Protocols?”

Kevin Hosseini’s painting of his tutor’s dog, Bella.

Physicians should provide women considering abortion after Down syndrome screening with unbiased information and not attempt to influence their decision.

The harms of communicating autism risk can be avoided by helping families to understand risk and to distinguish between poor and good sources of scientific information, which should take families’ interests into account.

Authors argue that use of nonhuman primates and other animals is unjustified.

In treating children with autism, physicians should reframe the common dynamic in which the family wants medication that the doctor is withholding to focus instead on the family’s and physician’s share goal—the patient’s well-being.